[Conjunctival squamous cell carcinoma: paradoxical response to interferon eyedrops].
نویسندگان
چکیده
CASE REPORT A 67 year-old male seen for a longstanding corneal-conjunctival tumor. TREATMENT topical interferon α2b (IFN-α2b) 10 U/ml. A significant increase in lesion size was observed after 8 weeks. A surgical excision with cryotherapy was then performed. Pathological examination confirmed the diagnosis of squamous cell carcinoma. At this time the patient was found to have a positive HIV serology. DISCUSSION Conjunctival intraepithelial neoplasia (CIN) is a pre-cancerous lesion of the ocular surface. Medical treatment of CIN is essentially with IFN-α2b due to its antiviral/antitumor properties. In patients with HIV, treatment response could be paradoxical. We recommend serology for HIV before treatment with topical IFN-α2b.
منابع مشابه
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ورودعنوان ژورنال:
- Archivos de la Sociedad Espanola de Oftalmologia
دوره 89 7 شماره
صفحات -
تاریخ انتشار 2014